Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Restlessness
ADR ID BADD_A03825
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.021      Restlessness
19      Psychiatric disorders
19.11      Changes in physical activity
19.11.02      Increased physical activity levels
19.11.02.002      Restlessness
Description A disorder characterized by an inability to rest, relax or be still. [CTCAE] A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. [MeSH]
MedDRA Code 10038743
MeSH ID D011595; D011595; D011595
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Marked restlessness | Muscular unrest | Physical wandering | Physically restless | Psychomotor restlessness | Restless | Restlessness | Restlessness (drug related) | Restlessness (phenothiazine) | Restlessness marked | Unrest | Wandering | Wandering around | Restlessness aggravated | Psychomotor Agitation | Psychomotor Hyperactivity | Hyperactivity, Psychomotor | Psychomotor Restlessness | Restlessness, Psychomotor | Agitation, Psychomotor | Excitement, Psychomotor | Psychomotor Excitement | Akathisia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00880Fentanyl citrate--
BADD_D00898Finasteride0.000534%
BADD_D00932Fluoxetine0.001225%
BADD_D00936Fluphenazine decanoate--
BADD_D00937Fluphenazine hydrochloride--
BADD_D00940Flurazepam hydrochloride--
BADD_D00952Folic acid0.000235%
BADD_D00979Furosemide0.000222%
BADD_D00981Gabapentin0.000661%
BADD_D00995Gadoxetate disodium--
BADD_D01009Gemcitabine--
BADD_D01012Gemfibrozil0.000460%
BADD_D01023Glimepiride0.000191%
BADD_D01037Gonadotrophin chorionic--
BADD_D01051Halobetasol--
BADD_D01054Haloperidol0.013231%
BADD_D01055Haloperidol decanoate--
BADD_D01056Haloperidol lactate--
BADD_D01066Hetastarch--
BADD_D01081Hydralazine0.000331%
BADD_D01083Hydrochlorothiazide--
BADD_D01093Hydroflumethiazide--
BADD_D01099Hydroxocobalamin--
BADD_D01111Hydroxyzine0.000260%
BADD_D01119Ibrutinib--
BADD_D01120Ibuprofen0.000037%
BADD_D01132Idursulfase--
BADD_D01134Iloperidone--
BADD_D01136Imatinib--
BADD_D01140Imipramine hydrochloride--
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